細(xì)胞名稱

人急性非B非T淋巴細(xì)胞白血病細(xì)胞Reh

貨物編碼

BFN60806597

產(chǎn)品規(guī)格

T25培養(yǎng)瓶x1

1.5ml凍存管x2

細(xì)胞數(shù)量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運(yùn)輸方式

常溫保溫運(yùn)輸

干冰運(yùn)輸

安全等級

1

用途限制

僅供科研           2類

培養(yǎng)體系

DMEM高糖+10%FBS+1%雙抗

培養(yǎng)溫度

37℃

二氧化碳濃度

5%

簡介

人急性非B非T淋巴細(xì)胞白血病細(xì)胞Reh取自15歲女性供體，該細(xì)胞源于ATCC

序列突變

/

注釋

Part of: Cancer Cell Line Encyclopedia (CCLE) project.

Part of: COSMIC cell lines project.

Part of: LL-100 blood cancer cell line panel.

Part of: MD Anderson Cell Lines Project.

Doubling time: 34.7 hours (PubMed=8847894); 30 hours (PubMed=25984343); ~50-70 hours (DSMZ).

Microsatellite instability: Instable (MSI-high) (PubMed=31068700; Sanger).

Omics: Array-based CGH.

Omics: Deep antibody staining analysis.

Omics: Deep exome analysis.

Omics: Deep quantitative phosphoproteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: Deep RNAseq analysis.

Omics: DNA methylation analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: shRNA library screening.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

Derived from sampling site: Peripheral blood.

STR信息

Amelogenin        X

CSF1PO        10,11,12 (AddexBio; ATCC; PubMed=25877200)

12,13 (CLS; Cosmic-CLP; DSMZ)

D3S1358        18

D5S818        11,13 (AddexBio; ATCC; PubMed=25877200)

11,12,13 (CLS)

11,12 (Cosmic-CLP; DSMZ)

D7S820        9,12 (AddexBio; ATCC; Cosmic-CLP; DSMZ; PubMed=25877200)

9,10,12,13 (CLS)

D8S1179        13,14,16,17 (CLS)

13,15 (PubMed=25877200)

D13S317        11,13 (AddexBio; ATCC; PubMed=25877200)

11,12,13 (CLS)

11,14 (Cosmic-CLP)

10,11,14 (DSMZ)

D16S539        9 (AddexBio; ATCC; PubMed=25877200)

9,10,12,13 (CLS)

9,13 (Cosmic-CLP; DSMZ)

D18S51        10,11,14 (CLS)

10,14 (PubMed=25877200)

D21S11        28,29,30,31 (CLS)

28,30 (PubMed=25877200)

FGA        22,23,24 (CLS)

22,23 (PubMed=25877200)

Penta D        9,12 (CLS)

9,11 (PubMed=25877200)

Penta E        10,11 (CLS)

7,11 (PubMed=25877200)

TH01        7 (AddexBio; ATCC; CLS; PubMed=25877200)

7,9 (Cosmic-CLP; DSMZ)

TPOX        8

vWA        14,15 (AddexBio; ATCC; Cosmic-CLP; PubMed=25877200)

14,15,16 (CLS; DSMZ)

參考文獻(xiàn)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3

Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Nature 569:503-508(2019)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x

Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.

The LL-100 panel: 100 cell lines for blood cancer studies.

Sci. Rep. 9:8218-8218(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023

Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E., Schweppe D.K., Jedrychowski M., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.

Quantitative proteomics of the Cancer Cell Line Encyclopedia.

Cell 180:387-402(2020)